3-Nitro-2(1<i>H</i>)-quinolone derivatives as 2π components in 1,3-dipolar cycloadditions of azomethine ylides: A new synthesis of pyrrolo[3,4-<i>c</i>]quinolines
نویسندگان
چکیده
The 1,3-dipolar cycloaddition of 3-nitro-2(1H)-quinolones with ester-stabilized azomethine ylides derived from sarcosine ester and various aromatic aldehydes has been investigated. structure stereochemistry cycloadducts were studied in detail by X-ray NMR spectroscopy methods.
منابع مشابه
Catalytic Enantioselective 1,3-Dipolar Cycloadditions of Azomethine Ylides for Biology-Oriented Synthesis
Cycloaddition reactions are among the most powerful methods for the synthesis of complex compounds. In particular, the development and application of the 1,3-dipolar cycloaddition, an important member of this reaction class, has grown immensely due to its powerful ability to efficiently build various five-membered heterocycles. Azomethine ylides are commonly used as dipoles for the synthesis of...
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The development of multicomponent reactions (MCRs) designed to produce elaborate biologically active compounds has become an important area of research in organic, combinatorial, and medicinal chemistry. A comparative study of the synthesis of new bis-spiro-oxindolo(pyrrolizidines/pyrrolidines) ring systems by the cycloaddition of azomethine ylides generated by a decarboxylative route from sarc...
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ژورنال
عنوان ژورنال: Synthetic Communications
سال: 2022
ISSN: ['1532-2432', '0039-7911']
DOI: https://doi.org/10.1080/00397911.2022.2150976